> ## Documentation Index
> Fetch the complete documentation index at: https://docs.boltz.bio/llms.txt
> Use this file to discover all available pages before exploring further.

# Results and Triage

> Evaluate and organize protein binder candidates

## Overview

After a virtual screen completes, candidates are available in your experiment for evaluation, triage, and further analysis.

## Experiment View

<Frame>
  <img src="https://mintcdn.com/boltzpbc/EKeBMCVOgldAcowK/images/user-guide/protein-design/results-2.png?fit=max&auto=format&n=EKeBMCVOgldAcowK&q=85&s=b453c77b3373389f9236cde803065df6" alt="New protein design screen form" width="1416" height="873" data-path="images/user-guide/protein-design/results-2.png" />
</Frame>

The experiment view provides three tabs:

* **Overview** - Summary statistics and metrics
* **Table** - List view of all candidates with filters and sorting
* **Triage** - Organized view for candidate evaluation

## Candidate Table

Each candidate row shows:

* **Sequence** - Protein sequence with CDR regions highlighted (for antibodies/nanobodies)
* **Id** - Unique identifier (e.g., NB-X7CMZA38)
* **Triage** - Thumbs down, flag, and thumbs up counts
* **Created By** - Which virtual screen generated this candidate
* **Created** - Timestamp when the candidate was generated
* **Binding Confidence** - Predicted binding affinity score for the target
* **Structure Confidence** - Overall structure quality score

### Filtering and Selection

* **Default view** dropdown - Pre-configured filter sets
* **Columns** button - Show/hide table columns
* **Filters** button - Add custom filters including:
  * **Text filters** - Filter by Id, Created By, etc.
  * **Number filters** - Filter by ipTM, pLDDT, Binding Confidence, Structure Confidence, Loop Fraction using sliders
  * Filter chips show active filters and can be removed individually
* **Select candidates** - Use checkboxes to select multiple candidates
* **Download** - Export selected candidates

### Bulk Actions

When candidates are selected:

* **Add to experiment** - Move to another experiment
* **Tag** - Apply tags for organization
* **Download** - Export candidate data

## 3D Visualization

The right panel shows:

### Target Selection

* Dropdown to switch between targets
* Selected candidate IDs displayed as colored tags
* Download and fullscreen options

### 3D Structure Viewer

* Interactive 3D ribbon diagram showing:
  * **Target** (light grey)
  * **Binder candidates** (colored by selection)
* 3D axis indicator for orientation
* Rotate, zoom, and pan controls

### Properties Comparison

Compare metrics across selected candidates:

* **ipTM** - Interface predicted Template Modeling score
* **pLDDT** - Predicted Local Distance Difference Test (structure confidence)
* **Binding Confidence** - Predicted binding affinity
* **Structure Confidence** - Overall structure quality

Each chart shows all selected candidates as colored lines, making it easy to identify top performers.

## Triage View

The **Triage** tab provides a detailed view for evaluating individual candidates:

### Left Panel - Candidate Details

* **Sequence Viewer:**
  * Full protein sequence with Framework Regions (FR) and Complementarity Determining Regions (CDR) highlighted
  * CDR regions color-coded (CDR1, CDR2, CDR3)
  * Residue numbers displayed above sequence
  * Navigation arrows to move between candidates

* **Candidate Actions:**
  * **Star** - Favorite a candidate
  * **Thumbs down** - Reject candidate
  * **Flag** - Mark for further review
  * **Thumbs up** - Approve candidate
  * **+ Tag** - Apply tags for organization

* **Properties and Descriptors:**
  * **Properties tab** - View metrics (ipTM, pLDDT, Binding Confidence, Structure Confidence)
  * **Descriptors tab** - View structural features (Loop Fraction, Helix Fraction, Sheet Fraction)
  * Switch between **Table** and **Plot** views for each

### Right Panel - 3D Structure and Comparison

* **3D Structure Viewer:**
  * Shows the selected candidate's binding pose with the target
  * Binder colored orange, target colored light grey/green
  * Interactive controls for rotation, zoom, and pan

* **Properties Comparison:**
  * Parallel coordinates plot showing all candidates
  * Selected candidate highlighted in purple
  * Non-selected candidates shown in dark grey
  * Compare across multiple properties simultaneously

## Triage Workflow

1. **Select candidates** - Use checkboxes or filters to narrow down
2. **Review 3D structures** - Examine binding poses in the viewer
3. **Compare properties** - Use charts to identify high-scoring candidates
4. **Triage actions:**
   * **Thumbs down** - Reject candidate
   * **Flag** - Mark for further review
   * **Thumbs up** - Approve candidate
5. **Tag candidates** - Apply tags for organization (e.g., "high-affinity", "interesting-pose")
6. **Export** - Download selected candidates for further analysis

## Tips

* Start by filtering to top performers (high binding confidence)
* Review 3D structures to ensure poses are reasonable
* Compare multiple candidates side-by-side using the properties charts
* Use tags to organize candidates by different criteria
* Export promising candidates for experimental validation